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In populations who cannot exercise due to frailty, physical disability, or cardiovascular limitations, MOTS-c represents one of the most compelling candidates in the emerging class of pharmacological exercise mimetics
The compound is intended strictly for in vitro and preclinical laboratory investigation and should never be used outside a research context
There is some research to suggest it can cause issues in people who have kidney problems
In research models, this inhibition indirectly preserves NAD by reducing methylation of nicotinamide, and also maintains SAM levels an effect precursors do not address
